THROMBOSIS AND HEMOSTASIS Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men
نویسندگان
چکیده
1Department of Plasma Proteins, Sanquin Research, Amsterdam; 2Department of Clinical Chemistry and Haematology, Thrombosis and Haemostasis Laboratory, University Medical Center, Utrecht; 3Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht; 4Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht; 5Department of Clinical Epidemiology, Leiden University Medical Center, Leiden; 6Thrombosis and Haemostasis Research Center, Department of Haematology, Leiden University Medical Center, Leiden; 7Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden; and 8Department of Health Technology & Services Research, University of Twente, Enschede, The Netherlands
منابع مشابه
Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men
AIMS The extent to which hemostatic and inflammatory biomarkers are related to angina pectoris as compared with myocardial infarction (MI) remains uncertain. We examined the relationship between a wide range of inflammatory and hemostatic biomarkers, including markers of activated coagulation, fibrinolysis and endothelial dysfunction and viscosity, with incident myocardial infarction (MI) or co...
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Elevated circulatory levels of many blood coagulation factors are known to be a risk factor for deep vein thrombosis in humans. Here we report the first direct demonstration of a close association between elevated circulatory factor IX levels in mice with thrombosis as well as myocardial fibrosis. Transgenic mice overexpressing human factor IX at persistently high levels died at much younger ag...
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متن کاملLeft running head: MELTZER et al Right running head: FIBRINOLYSIS AND RISK OF MYOCARDIAL INFARCTION Scientific section designation: CLINICAL TRIALS AND OBSERVATIONS Plasma levels of fibrinolytic proteins and the risk of myocardial infarction in men
Mirjam E. Meltzer, Carine J.M. Doggen, Philip G. de Groot, Frits R. Rosendaal, MD, and Ton Lisman Department of Clinical Chemistry and Hematology, University Medical Center Utrecht; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden; 3 Department of Health Technology and Services Research, School for Management and Governance, University of Twente, Enschede; Departmen...
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